MICAL — a missing link

Embryonic PCNA: a missing link?

PCNA, the processivity factor of the eukaryotic replicative DNA polymerase [1], is the functional homolpgue of the [3 subunit of Escherichia coli DNA polymerase III holo-enzyme [2,3]. Biochemical studies have shown that the E. coli 3 subunit acts as a sliding clamp on duplex DNA; it has a ring shape that encircles DNA and it binds directly to Pol III, tethering it to DNA to achieve highly proce...

loving and humane care: a missing link in nursing

“vitality” a missing link in adjustment to childhood cancer

background: a number of randomized trial studies and longitudinal researches emphasize that despite problems in social adjustment and cognitive damages, children with cancer demonstrate good emotional adjustment. methods: most of the research findings in this area are obtained using objective tools such as questionnaires. “vitality of children”, as a drawing tool, was used as a basis to draw a ...

Fiscal Space Assessment: A Missing Link in Financing Management of Iran’s Health System

Fiscal Space Assessment: A Missing Link in Financing Management of Iran’s Health System Nader Jahanmehr1,2, Soheila Damiri3*, Reza Goudarzi4, Zhaleh Abdi5 1 School of Management and Medical Education, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2 Prevention of Cardiovascular Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3 Department of...

Finding the missing link

The discovery of an ancient protein complex reveals the evolutionary relationships between the proteins that help to form vesicles.